Clinical observation of the combination of benazepril and valsartan in the treatment of diabetic nephropathy

Objective:To investigate the clinical efficacy of the combination of benazepril and valsartan in the treatment of diabetic nephropathy. Methods:Collected 81 patients with diabetic nephropathy in Ⅳ phase in our hospital, who were randomly divided into three groups, each group had 27 cases, the treatment group complied with the combination of benazepril and valsartan, the control group respectively treated with benazepril and valsartan. Observed and recorded the blood pressure, 24 hours of urinary protein quantitative, blood urea nitrogen (BUN), creatinine (Scr), blood potassium and blood glucose etc. various changes in the indicators before and after the treatment. Results:After the treatment of 12 weeks, blood pressure and 24 hours of urinary protein quantitative in each group declined significantly (P0.05), and the treatment group was better than the control groups, the difference had statistics significance (P0.05). Conclusion:Combination of benazepril and valsartan on treating diabetic nephropathy can obviously decrease urinary protein, control blood pressure, enhance the curative effect.