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The clinical value of B type natriuretic peptide in patients with congestive heart failure

LI Qingying

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Abstract

【Objective】To investigate the clinical value of B type natriuretic peptide(BNP) in patients with congestive heart failure(CHF).【Methods】96 patients were admitted to hospital for CHF.BNP levels,left ventricular ejection fraction(LVEF),left ventricular end diastolic diameters(LVDD) were performed respectively in admission and before discharge.【Results】BNP levels were significantly different in different heart function classes according to NYHA(P0.001).The levels of BNP in patients with heart function class Ⅰ,Ⅱ,Ⅲ and Ⅳwere(127±15) pg/ml,(352±29) pg/ml,(580±31) pg/ml and(1045±38) pg/ml,respectively.There was a significant negative correlation between BNP levels and LVEF(r=-0.8,P0.05).【Conclusion】BNP is a good marker to left ventricular function.

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What this paper is about

【Objective】To investigate the clinical value of B type natriuretic peptide(BNP) in patients with congestive heart failure(CHF).【Methods】96 patients were admitted to hospital for CHF.BNP levels,left ventricular ejection fraction(LVEF),left ventricular end diastolic diameters(LVDD) were performed respectively in admission and before discharge.【Results】BNP levels were significantly different in different heart function classes according to NYHA(P0.001).The levels of BNP in patients with heart function class Ⅰ,Ⅱ,Ⅲ and Ⅳwere(127±15) pg/ml,(352±29) pg/ml,(580±31) pg/ml and(1045±38) pg/ml,respectively.There was a significant negative correlation between BNP levels and LVEF(r=-0.8,P0.05).【Conclusion】BNP is a good marker to left ventricular function.

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Available abstract

【Objective】To investigate the clinical value of B type natriuretic peptide(BNP) in patients with congestive heart failure(CHF).【Methods】96 patients were admitted to hospital for CHF.BNP levels,left ventricular ejection fraction(LVEF),left ventricular end diastolic diameters(LVDD) were performed respectively in admission and before discharge.【Results】BNP levels were significantly different in different heart function classes according to NYHA(P0.001).The levels of BNP in patients with heart function class Ⅰ,Ⅱ,Ⅲ and Ⅳwere(127±15) pg/ml,(352±29) pg/ml,(580±31) pg/ml and(1045±38) pg/ml,respectively.There was a significant negative correlation between BNP levels and LVEF(r=-0.8,P0.05).【Conclusion】BNP is a good marker to left ventricular function.

Key concepts: Heart failure, Ejection fraction, Cardiology, Internal medicine, Natriuretic peptide, Medicine, Diastole, Ventricular function

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