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Effect of brain natriuretic peptide on chronic heart failure

Wang Min-hong

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Abstract

Objective:To investigate the value of brain natriuretic peptide(BNP) on heart function evaluation in patients with chronic heart failure(CHF).Methods:A total of 148 patients with chronic heart failure in different NYHA class were study,whose blood BNP concentrations were measured with Triage BNP test;blood BNP concentrations also measured by the same way in some patients with NHYA class Ⅲ,Ⅳ after one to four weeks treatment for heart failure.Results:There were remarkable difference in level of blood BNP among CHF patients with different NYHA class[class Ⅱ(362±192)pg/ml,class Ⅲ(792±318)pg/ml,class Ⅳ(2156±1065)pg/ml,P0.01].After treatment for heart failure,with the improving of heart function,the level of BNP declined obviously from(2153±1067)pg/ml to (1012±564)pg/ml,(P0.01).Conclusion:BNP as a objective index is significant for heart function and prognoses evaluation.

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What this paper is about

Objective:To investigate the value of brain natriuretic peptide(BNP) on heart function evaluation in patients with chronic heart failure(CHF).Methods:A total of 148 patients with chronic heart failure in different NYHA class were study,whose blood BNP concentrations were measured with Triage BNP test;blood BNP concentrations also measured by the same way in some patients with NHYA class Ⅲ,Ⅳ after one to four weeks treatment for heart failure.Results:There were remarkable difference in level of blood BNP among CHF patients with different NYHA class[class Ⅱ(362±192)pg/ml,class Ⅲ(792±318)pg/ml,class Ⅳ(2156±1065)pg/ml,P0.01].After treatment for heart failure,with the improving of heart function,the level of BNP declined obviously from(2153±1067)pg/ml to (1012±564)pg/ml,(P0.01).Conclusion:BNP as a objective index is significant for heart function and prognoses evaluation.

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Available abstract

Objective:To investigate the value of brain natriuretic peptide(BNP) on heart function evaluation in patients with chronic heart failure(CHF).Methods:A total of 148 patients with chronic heart failure in different NYHA class were study,whose blood BNP concentrations were measured with Triage BNP test;blood BNP concentrations also measured by the same way in some patients with NHYA class Ⅲ,Ⅳ after one to four weeks treatment for heart failure.Results:There were remarkable difference in level of blood BNP among CHF patients with different NYHA class[class Ⅱ(362±192)pg/ml,class Ⅲ(792±318)pg/ml,class Ⅳ(2156±1065)pg/ml,P0.01].After treatment for heart failure,with the improving of heart function,the level of BNP declined obviously from(2153±1067)pg/ml to (1012±564)pg/ml,(P0.01).Conclusion:BNP as a objective index is significant for heart function and prognoses evaluation.

Key concepts: Medicine, Heart failure, Internal medicine, Brain natriuretic peptide, Cardiology, Natriuretic peptide

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