Application of 256 slice spiral CT perfusion imaging in middle cerebral artery stenosis or occlusion

Objective To explore the value of clinical application of 256 slice spiral CT perfusion(CTP) combined with angiography(CTA) in patients with stenosis or occlusion of middle cerebral artery(MCA). Methods Thirtyone patients underwent joint inspection of CTA and CTP. The patients were divided into three levels: mild, moderate and severe according to the degree of carotid artery stenosis. Cerebral blood flow(rCBF), cerebral blood volume(rCBV), mean transit time(MTT) and time to peak(TTP) of injured and the uninjured side were measured and compared. Results The differences of rCBF, MTT and TTP of the watershed area were statistically significant(P 0.01);there was no significant difference in rCBV(P 0.05). Basal ganglia rCBV, rCBF, MTT and TTP differences were highly statistically significant(P 0.01). Conclusions Affected by collateral circulation and other factors, there is correlation of middle cerebral artery severe stenosis or occlusion with the blood perfusion reduction, but no apparent correlation of mild to moderate stenosis with cerebral perfusion reduction.