Clinical study of Duhuo Jisheng Decoction in the treatment of degenerative knee arthritis

Objective To investigate the clinical efficacy of Duhuo Jisheng decoction in the treatment of degenerative knee arthritis.Methods 60 cases of patients with knee osteoarthritis were randomly divided into treatment group(30 cases,taking Duhuo Jisheng Decoction) and control group(30 patients,taking celecoxib).Lysholm score and interleukin-1 knee synovial fluid content of the two groups after treatment were determined and compared to evaluate the clinical efficacy of Duhuo Jisheng Decoction.Results Lysholm score of the control group after treatment was(75.5±4.5) scores,while that of the treatment group was(88.5±5.5) scores,demonstrating a significant difference(P 0.05);interleukin-1 knee synovial fluid of the control group after treatment had an average of(365.44±28.9) pg/mL,white that of the treatment group averaged(305.44±31.4) pg/mL,there was significant difference(P 0.05).Conclusion Duhuo Jisheng Decoction in the treatment of degenerative knee arthritis can significantly improve patients' Lysholm score,and reduce the content of interleukin-1 in patients' knee synovial fluid at the same time.The clinical efficacy is obvious,thus its application is worth promoting.