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2001•Ningxia Medical JournalRequires access

A study of Marine (Oxymatrine) treatment chronic hepatitis B

Ya Liu

Open publisher page 1 citations

Abstract

Objectives To study Marine (Oxymatrine) treatment chronic hepatitis B of appropriate does and the long-term efficacy.Methods Marine (Oxymatrine) Ⅰgroup (400mg) treatment 74 patients with chronic hepatitis B, Ⅱgroup (600mg) treatment 90 patients with chronic hepatitis B , compare with α-IFN treatment 75 patients with chronic hepatitis B, while visiting one year.Results HBeAg loss and HBV-DNA loss of Marine (Oxymatrine) I group (400mg) was 32.4% and 37.8%, Ⅱgroup (600mg) was 36.7% and 40.0%; α-IFN group was 41.3% and 44.0% (p0.05). After visiting one year, HBeAg loss and HBV-DNA loss of Marine (Oxymatrine) I group (400mg) was 36.1% and 27.9%; Ⅱgroup (600mg) was 38.5% and 29.5%;α-IFN group was 42.4%and 42.4%(p0.05).Conclusions To two groups patients with chronic hepatitis B, Marine (Oxymatrine) treatment were better and didnt find out side-effection. So Marine (Oxymatrine) treatment chronic hepatitis B is as good asα-IFN,is a helpful kind of durg treatment chronic hepatitis B.

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Objectives To study Marine (Oxymatrine) treatment chronic hepatitis B of appropriate does and the long-term efficacy.Methods Marine (Oxymatrine) Ⅰgroup (400mg) treatment 74 patients with chronic hepatitis B, Ⅱgroup (600mg) treatment 90 patients with chronic hepatitis B , compare with α-IFN treatment 75 patients with chronic hepatitis B, while visiting one year.Results HBeAg loss and HBV-DNA loss of Marine (Oxymatrine) I group (400mg) was 32.4% and 37.8%, Ⅱgroup (600mg) was 36.7% and 40.0%; α-IFN group was 41.3% and 44.0% (p0.05). After visiting one year, HBeAg loss and HBV-DNA loss of Marine (Oxymatrine) I group (400mg) was 36.1% and 27.9%; Ⅱgroup (600mg) was 38.5% and 29.5%;α-IFN group was 42.4%and 42.4%(p0.05).Conclusions To two groups patients with chronic hepatitis B, Marine (Oxymatrine) treatment were better and didnt find out side-effection. So Marine (Oxymatrine) treatment chronic hepatitis B is as good asα-IFN,is a helpful kind of durg treatment chronic hepatitis B.

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Available abstract

Objectives To study Marine (Oxymatrine) treatment chronic hepatitis B of appropriate does and the long-term efficacy.Methods Marine (Oxymatrine) Ⅰgroup (400mg) treatment 74 patients with chronic hepatitis B, Ⅱgroup (600mg) treatment 90 patients with chronic hepatitis B , compare with α-IFN treatment 75 patients with chronic hepatitis B, while visiting one year.Results HBeAg loss and HBV-DNA loss of Marine (Oxymatrine) I group (400mg) was 32.4% and 37.8%, Ⅱgroup (600mg) was 36.7% and 40.0%; α-IFN group was 41.3% and 44.0% (p0.05). After visiting one year, HBeAg loss and HBV-DNA loss of Marine (Oxymatrine) I group (400mg) was 36.1% and 27.9%; Ⅱgroup (600mg) was 38.5% and 29.5%;α-IFN group was 42.4%and 42.4%(p0.05).Conclusions To two groups patients with chronic hepatitis B, Marine (Oxymatrine) treatment were better and didnt find out side-effection. So Marine (Oxymatrine) treatment chronic hepatitis B is as good asα-IFN,is a helpful kind of durg treatment chronic hepatitis B.

Key concepts: Oxymatrine, Medicine, Chronic hepatitis, HBeAg, Internal medicine, Gastroenterology, Hepatitis B, Hepatitis

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