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2005•Chinese Journal of Clinical NeurosciencesRequires access

Evaluation of the Clinical Effect in the Treatment of Acute Cerebral Infarctions with ShiJieYin(GM_1)

Ding Su

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Abstract

Aim:To evaluate the clinical curative effect and safety of ganglioside GM1 in treatment of acute cerebral infarctions. Methods:96 patients from the onset within 72 h were randomly divided into two groups:the ganglioside GM1 treated group and control group. The Chinese Stroke Scale (CSS),Barthel Index (BI) ,and Rankin Scale were used to evaluate the recovery of neurological functions.Results:The obvious effective rate of the therapy group was 52.08%,response rate was 31.25%. Whereas,these data of the control group were 25.00% and 52.08%,respectively.The Barthel Index significantly changed in treatment group(P0.05) . Rankin Scale at 3 months after initiation significantly decreased in treatment group. Conclusion:Ganglioside GM1 is effective and relative safety in treatment of acute cerebral infarctions.

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What this paper is about

Aim:To evaluate the clinical curative effect and safety of ganglioside GM1 in treatment of acute cerebral infarctions. Methods:96 patients from the onset within 72 h were randomly divided into two groups:the ganglioside GM1 treated group and control group. The Chinese Stroke Scale (CSS),Barthel Index (BI) ,and Rankin Scale were used to evaluate the recovery of neurological functions.Results:The obvious effective rate of the therapy group was 52.08%,response rate was 31.25%. Whereas,these data of the control group were 25.00% and 52.08%,respectively.The Barthel Index significantly changed in treatment group(P0.05) . Rankin Scale at 3 months after initiation significantly decreased in treatment group. Conclusion:Ganglioside GM1 is effective and relative safety in treatment of acute cerebral infarctions.

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Available abstract

Aim:To evaluate the clinical curative effect and safety of ganglioside GM1 in treatment of acute cerebral infarctions. Methods:96 patients from the onset within 72 h were randomly divided into two groups:the ganglioside GM1 treated group and control group. The Chinese Stroke Scale (CSS),Barthel Index (BI) ,and Rankin Scale were used to evaluate the recovery of neurological functions.Results:The obvious effective rate of the therapy group was 52.08%,response rate was 31.25%. Whereas,these data of the control group were 25.00% and 52.08%,respectively.The Barthel Index significantly changed in treatment group(P0.05) . Rankin Scale at 3 months after initiation significantly decreased in treatment group. Conclusion:Ganglioside GM1 is effective and relative safety in treatment of acute cerebral infarctions.

Key concepts: Barthel index, Modified Rankin Scale, Medicine, Ganglioside, Anesthesia, Treatment and control groups, Cerebral infarction, Neuroprotection

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