A clinical study on the effects of early intensive blood pressure reduction on short-term prognosis of hypertensive intracerebral hemorrhage

Objective To study and explore the effects of early intensive blood pressure reduction on short-term prognosis of hypertensive intracerebral hemorrhage. Methods 90 patients with acute intracerebral hemorrhage who were admitted to the Guangdong Lianzhou People's Hospital from June 2011 to February 2013 were selected and randomly and evenly assigned into a group of active blood pressure reduction and a group of guideline blood pressure reduction.Patients' blood pressure had been monitored since admission. Patients' degrees of neurologic impairment,activities of daily living and Glasgow coma scores on admission were recorded. Conditions of symptoms alleviation and hematomas were also recorded before and after the treatment.Clinical prognoses in 2,14 and 30 days after the onset in the two groups were observed.Patients' degrees of neurologic impairment and clinical effects were then evaluated and compared. Results NHISS scores in 14 days and 30 days after the treatment,total effective rate, BI scores in 14 days and 30 days after the treatment were 8.5±9.6, 5.8±7.6,82.22%,43.56±31.45, 60.00±33.45 respectively in the group of active blood pressure reduction. Those data in the group of guideline reduction were 10.1±11.7,7.1±10.4,53.33%, 40.45±29.75,49.35±29.50 respectively.All data in the group of active reduction were significantly better than those in the group of guideline reduction(P 0.05). Conclusion Early and active blood pressure control in the treatment of hypertensive intracerebral hemorrhage has the effects of cerebral protection,curbs hematoma enlargement and pathological damages,promotes the recovery of neurological functions,and reduces disability and mortality rate.