Clinical Analysis of Yishen Lishi Decoction in Treating Refractory nephritic Syndrome patients

Objective: To observe the clinical curative effect on treatment in treating 21 cases of refractory nephritic syndrome(RNS). Methods :42 in and out-patients with RNS were randomly divided into groups. Inside the treatment group, the cases were treated with both Yishen Lishi Decoction and western medicine, while the control group was only treated with western medicine. For the two groups, The observation was made to see the changes of 24Hours urine protein quantity(24hUPQ), blood ureanitrogen (BUN), serum creatinine (Scr), cholesterol (CHOL), triglyceride (TG), and serum albumin (ALB) before and after the treatment. Results: The total effective rate in the treatment group reached 94.4%,significantly higher than that in the control group(75%,P0.05). In both groups, after the treatment, ALB was increased, except TG, 24h UPQ ,BUN, Scr , CHOL were decreased (P0.01~0.05).In the treatment group , the improvement was observed obviously when compared with the control group .Conclusion: Yishen Lishi Decoction can enhance the clinical curative effect and reduce a certain side effect in treating refractory nephritic syndrome by hormone.