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2012•Chinese Journal of Birth Health & HeredityRequires access

Establishment of thyroid stimulating hormone(TSH) cut-off value for newborn congenital hypothyroidism(CH) screening in suqian,Jiangsu

Cen Ming-xin

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Abstract

Objective: To establish cut-off value of thyroid stimulating hormone(TSH) screening for congenital hypothyroidism(CH) in Suqian city.Methods: By statistic analyzing 127,767 cases of neonatal TSH test data obtained during the past 18 months,TSH cut-off value of this region was determined by percentage method.Performance of the new cut-off value was assessed too.Results: The results identified that TSH cut-off should be set at 8.0μU/ml.With the new cut-off value,newborns to be recalled for retest increased by 382 cases,1 case of leakage can be avoided.Conclusion: 8.0μU/ml is more suitable for Suqian city.

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What this paper is about

Objective: To establish cut-off value of thyroid stimulating hormone(TSH) screening for congenital hypothyroidism(CH) in Suqian city.Methods: By statistic analyzing 127,767 cases of neonatal TSH test data obtained during the past 18 months,TSH cut-off value of this region was determined by percentage method.Performance of the new cut-off value was assessed too.Results: The results identified that TSH cut-off should be set at 8.0μU/ml.With the new cut-off value,newborns to be recalled for retest increased by 382 cases,1 case of leakage can be avoided.Conclusion: 8.0μU/ml is more suitable for Suqian city.

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Available abstract

Objective: To establish cut-off value of thyroid stimulating hormone(TSH) screening for congenital hypothyroidism(CH) in Suqian city.Methods: By statistic analyzing 127,767 cases of neonatal TSH test data obtained during the past 18 months,TSH cut-off value of this region was determined by percentage method.Performance of the new cut-off value was assessed too.Results: The results identified that TSH cut-off should be set at 8.0μU/ml.With the new cut-off value,newborns to be recalled for retest increased by 382 cases,1 case of leakage can be avoided.Conclusion: 8.0μU/ml is more suitable for Suqian city.

Key concepts: Medicine, Congenital hypothyroidism, Thyroid, Thyroid-stimulating hormone, Hormone, Value (mathematics), Statistic, Pediatrics

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Establishment of thyroid stimulating hormone(TSH) cut-off value for newborn congenital hypothyroidism(CH) screening in suqian,Jiangsu — Research Paper | ScholarLens