Determination of nine trace elements in serum of breast tumor patient with graphito furmace atomic absorbtion spectrometry and its correlation factors

Objective The nine trace elements(Zn、Fe、Cu、Mn、Pb、Cd、Cr、Ni and Mo)Contents in serum were analysed. Methods Nine trace elements were measured with gitaphite furmace atomic absorbtion spectrometry in 213 healthy womon, 36 patients with benign breast disease and 38 patients with malignant bteast tumour before and after operation. Results There are five elements ertremely different in three groups of serum, The serum Zn Cu Ni and Fe contents were extremely higher but Mo was lower in malignant cases, concentrations were respectively postive and negtive correlation with disease progress of the disease, and the ratio of Cu/Zn in cancer group(1.48) was higer than that in control group. Conclusions Both the concentration of the trace elements and the relationship among them are different in benign tumor, malignant tumor of breast and healthy women.