2008•PubMedRequires access

[Studies on the chemical constituents of Lonicera macranthoides].

Xiaodong Jia, Xing-Zeng Zhao, Ming Wang, Yunfa Dong, Feng Xu

Abstract

OBJECTIVE: To study the chemical constituents of flower buds of Lonicera macranthoides. METHODS: The 90% EtOH extract of Lonicera macranthoides. was successively partitioned with petroleum ether and ethyl acetete. RESULTS: Repeated column chromatography of the ethyl acetete fraction afforded the following compounds (1-9): ginnol (1), triacontanol (2), ursolic acid (3), beta-sitosterol (4), triacontane (5), palmitic acid (6), beta-daucosterol (7), 3-decyl-3-octyldocosan-1-ol (8), 3-dodecyl-3-nonyldocosan-1-ol (9). All compounds except 4 are isolated from this plant for the first time while compounds 2, 3, 5, 8 and 9 are their first time been isolated from genus Lonicera.

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Key concepts: Chemistry, Petroleum ether, Ursolic acid, Palmitic acid, Chromatography, Chemical constituents, Daucosterol, Column chromatography