2003•PubMedRequires access

[Studies on chemical constituents in roots of Polygala tenuifolia].

Hao Wang, Yuxin Tong, Wen‐Cai Ye, Shouxun Zhao

Abstract

OBJECTIVE: To study the chemical constituents from the roots of Polygala tenuifolia. METHOD: Column chromatographic techniques were employed for isolation and purification of chemical constituents of the plant and the structures were elucidated by spectroscopic analysis. RESULT: Five chemical constituents were isolated and elucidated as 4-C-beta-glucopyranosyl-1,3,6-trihydroxy-7-methoxyxanthone (1), 4-C-[beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranosyl]-1,3,6- trihydroxy-7-methoxyxanthone (2), presenegenin (3), presenegenin-3-O-beta-D-glycopyranoside (4) and daucosterol (5), respectively. CONCLUSION: Compounds 1,3,4 and 5 were isolated from this plant for the first time. Compound 1 is a new natural product.

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Key concepts: Daucosterol, Chemical constituents, Chemistry, Natural product, Traditional medicine, Chromatography, Stereochemistry, Medicine