To Observe the Curative Effect of Trimetazidine on the Patients with Unstable Angina Pectoris and the Influence of Trimetazidine on C-reactive Protein

Objective To evaluate the curative effect of trimetazidine on the patients with unstable angina pectoris and the influence of trimetazidine on c-reactive protein(CRP).Methods 43 patients with unstable angina pectoris were divided into two groups by randomly: the controlled group(n=22)and the test group(n=21).In the controlled group,patients accepted the treatment with nitrate,β—blocker and aspirin,in the test group,trimetazidine were given in addition to conventional therapy.The treatment durations in both groups were 4 weeks.Evaluate the clinical effect and change of the electrocardiogram and the frequency and the lasting time of angina;at the same time,to detect the change of c-reactive protein level in serum of the patients with unstable angina pectoris.Results Two groups of patients with clinical efficacy difference was statistically significant(P0.05).Two groups of patients after treatment,the attack of angina frequency,duration difference was also statistically significant(P0.05).Conclusion Trimetazidine can obviously improve the clinical curative effect on the patients with unstable angina pectoris by notable depressing the level of CRP.