Analysis of endoscopic and pathological diagnosis of patients with gastric mucosa-associated lymphoid tissue lymphoma

To study the endoscopic and pathological features of gastric mucosa associated lymphoid tissue (MALT) lymphoma, reduce the rates of misdiagnosis and missed diagnosis, and improve accurate rate of diagnosis. The clinical, endoscopic and pathological datum of 32 patients with gastric MALT lymphoma diagnosed pathologically were analyzed retrospectively. Patients with gastric MALT lymphoma had a median age of 57.1 years with female predominance. The symptoms were not characteristic. The tumor commonly originated in the lower portion of gastric body and/or antrum in 90.6% of cases. After operation infiltrate serosa in 44.0% and range lymphatic metastasis in 32.0%. The tumors consisted of centrocyte-like cells, frequently accompanying with lymphoepithelial lesions and reactive lymph follicle. The correct diagnostic rate were 15.6% and 40.6% by endoscopy and pathology respectively. The correct diagnostic rate of postoperative pathological examination was up to 100%. Immunohistochemistry analysis showed B-cell lymphoma. [Conclusions] It is suggested that multiple deep biopsy, special pathological change and immunohistochemistry are helpful to correct diagnosis of gastric MALT lymphoma.