Cost-effectiveness Analysis of Cefepime and Ceftazidime in Treatment of Bacterial Infections

Objective: To evaluate the cost effectiveness and safety of cefepime and ceftazidime in treatment of bacterial infections. Methods: 129 patients with bacterial infections were recruited and randomized into cefepime group and ceftazidime group. Dosage regimens were cefepime 2g bid and ceftazidime 2g q8h; while for urinary tract infections, the dosages were that cefepime 1g bid and ceftazidime 1g tid. The pharmaceutical economics strategy was employed to make the cost effectiveness analysis. Results:The cost effectiveness of cefepime was lower than that of ceftazidime (72.3% Vs 68.8% of cure rate and 92.3% Vs 90.6% of efficacy rate) in the treatment of four kinds of bacterial infections. Conclusion:Cefepime is better than ceftazidime in the treatment of bacterial infections in regard to their cost effectiveness.