ScholarLens Back to search
2010•Shandong yiyaoRequires access

Inhibitory effects of nanosilver on influenza virus H3N2

Zheng Cong-long

Open publisher page 0 citations

Abstract

Objective To explore the inhibitory effects of nanosilver on influenza virus H3N2.Methods Inhibitory effects of nanosilver on influenza virus H3N2 were detected by hemagglutination test,MTT test,red cell attachment test and embryonated egg cultivation.Results The hemagglutination titer of influenza virus H3N2 in nanosilver group and the virus control group was less than 1∶4 and equal to 1∶1 024 respectively(P0.001).The maximal atoxic concentration of nanosilver and the tissue culture infective dose(TCID50) of H3N2 on MD-25 cell was 25 μg/ml and 10-3.5/0.1 ml respectively.The survival rate of MD-25 cells was(96.77±2.07)% after the 50 μg/ml nanosilver solution mixed with 40 TCID50 influenza virus H3N2 for 2 hours,and the survival rate of MD-25 cells was(33.09±1.48)% in 20 TCID50 influenza virus H3N2 group(P0.001).Conclusion Nanosilvers has obvious inhibitory effects on influenza virus H3N2.

About this research paper

What this paper is about

Objective To explore the inhibitory effects of nanosilver on influenza virus H3N2.Methods Inhibitory effects of nanosilver on influenza virus H3N2 were detected by hemagglutination test,MTT test,red cell attachment test and embryonated egg cultivation.Results The hemagglutination titer of influenza virus H3N2 in nanosilver group and the virus control group was less than 1∶4 and equal to 1∶1 024 respectively(P0.001).The maximal atoxic concentration of nanosilver and the tissue culture infective dose(TCID50) of H3N2 on MD-25 cell was 25 μg/ml and 10-3.5/0.1 ml respectively.The survival rate of MD-25 cells was(96.77±2.07)% after the 50 μg/ml nanosilver solution mixed with 40 TCID50 influenza virus H3N2 for 2 hours,and the survival rate of MD-25 cells was(33.09±1.48)% in 20 TCID50 influenza virus H3N2 group(P0.001).Conclusion Nanosilvers has obvious inhibitory effects on influenza virus H3N2.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the inhibitory effects of nanosilver on influenza virus H3N2.Methods Inhibitory effects of nanosilver on influenza virus H3N2 were detected by hemagglutination test,MTT test,red cell attachment test and embryonated egg cultivation.Results The hemagglutination titer of influenza virus H3N2 in nanosilver group and the virus control group was less than 1∶4 and equal to 1∶1 024 respectively(P0.001).The maximal atoxic concentration of nanosilver and the tissue culture infective dose(TCID50) of H3N2 on MD-25 cell was 25 μg/ml and 10-3.5/0.1 ml respectively.The survival rate of MD-25 cells was(96.77±2.07)% after the 50 μg/ml nanosilver solution mixed with 40 TCID50 influenza virus H3N2 for 2 hours,and the survival rate of MD-25 cells was(33.09±1.48)% in 20 TCID50 influenza virus H3N2 group(P0.001).Conclusion Nanosilvers has obvious inhibitory effects on influenza virus H3N2.

Key concepts: Embryonated, Virus, Hemagglutination, Titer, Hemagglutination assay, Virology, Inhibitory postsynaptic potential, Influenza A virus

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Inhibitory effects of nanosilver on influenza virus H3N2 — Research Paper | ScholarLens