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2006•Journal of Bengbu Medical CollegeRequires access

Clinical understand of sodium hyaluronate in the treatment of osteoarthritis of the knee

Zhou Jian-sheng

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Abstract

Objective:To observe the curative effect of 1% sodium hyaluronate(SH) injection in the treatment of osteoarthritis of the knee.Methods:SH injection was give 2 ml five times at intervals of one week through routine knee joint puncture,and compare Solu-Medrol sterile Powder(MP) injection was give 40 mg three times used the same ways.Results:The total effective rate was 94.2% after five weeks of etreatment in SH group.There was no recurrence of this disease in 88.4% of the patients 12 months after treatment.And in MP group,the total effective rate was 91.9%,83.8% of the patients who had been cured didn't recurrent after 12 months.Two groups is no significant difference(P0.05).Conclusions:SH injection is an effective drug for treatment of osteoarthritis of the knee.Its tenderness relief and no poision or less side effect.

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What this paper is about

Objective:To observe the curative effect of 1% sodium hyaluronate(SH) injection in the treatment of osteoarthritis of the knee.Methods:SH injection was give 2 ml five times at intervals of one week through routine knee joint puncture,and compare Solu-Medrol sterile Powder(MP) injection was give 40 mg three times used the same ways.Results:The total effective rate was 94.2% after five weeks of etreatment in SH group.There was no recurrence of this disease in 88.4% of the patients 12 months after treatment.And in MP group,the total effective rate was 91.9%,83.8% of the patients who had been cured didn't recurrent after 12 months.Two groups is no significant difference(P0.05).Conclusions:SH injection is an effective drug for treatment of osteoarthritis of the knee.Its tenderness relief and no poision or less side effect.

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Available abstract

Objective:To observe the curative effect of 1% sodium hyaluronate(SH) injection in the treatment of osteoarthritis of the knee.Methods:SH injection was give 2 ml five times at intervals of one week through routine knee joint puncture,and compare Solu-Medrol sterile Powder(MP) injection was give 40 mg three times used the same ways.Results:The total effective rate was 94.2% after five weeks of etreatment in SH group.There was no recurrence of this disease in 88.4% of the patients 12 months after treatment.And in MP group,the total effective rate was 91.9%,83.8% of the patients who had been cured didn't recurrent after 12 months.Two groups is no significant difference(P0.05).Conclusions:SH injection is an effective drug for treatment of osteoarthritis of the knee.Its tenderness relief and no poision or less side effect.

Key concepts: Medicine, Sodium hyaluronate, Osteoarthritis, Tenderness, Surgery, Knee Joint, Significant difference, Clinical efficacy

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