2010•Acta Medicinae SinicaRequires access

Clinical comparative analysis on schizophrenia treated with Aripiprazole and Colzapine

Liu Cai-xiu

Abstract

Objective: To explore the effect and safety of Aripiprazole and Clozapine in treating schizophrenia.Methods: 60 patients were randomly divided into Aripiprazole group and Clozapine group.The positive and negative symptoms were recorded before treatment and 1,2,4,6 and 8 weeks after treatment.The side-effect was evaluated by TESS.Results:No efficacy difference was found between the two groups.Patients in Aripiprazole group showed a good effect on recognition and negative symptoms,and the side-effect was also less than that of Clozapine group.Conclusion: Aripiprazole is safe,effective drug in treating schizophrenia.

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Key concepts: Aripiprazole, Clozapine, Schizophrenia (object-oriented programming), Medicine, Side effect (computer science), Drug, Internal medicine, Psychiatry