Distribution and drug resistance of pathogenic bacteria in lower respiratory tract infection

Objective To understand the distribution and drug resistance of pathogenic bacteria in lower respiratory tract infection in our hospital and to provide the basis for rational use of drugs.Methods The bacteria identification system of France biomerieux API was used in the bacterial identification.Drug sensitive tests was performed with paper stip method.Results 1 483 strains of pathogenic bacteria were separated from the sputum sample of 3802 cases and the number of strains of gram negative bacilli was 948,fungi were 296.Gram positive cocci were 237.The positive rate of Candida albicans was the highest followed by Klebsiella pneumoniae,Pseudomonas aeruginosa,staphylococcus aureus,Acinetobacter and escherichia coli.The drug-resistant rate of gram negative bacilli was the lowest to imipenem followed by cefoperazone/sulbactam,amikacin and ceftazidime.The drug-resistant rate of gram negative bacilli was the highest to sulfamethoxazole/trimethoprim followed by ampicillin,cefazolin and piperacillin.Staphylococci was sensitive(100%)to vancomycin and resistant(100%)to penicillin.Conclusion The lower respiratory tract infections are mainly caused by gram negative bacilli.Clinicians must use antibiotics reasonably depending on the results of drug sensitive tests.