Distribution and Drug Resistance of Pathogenic Bacteria in Patients With Respiratory Tract Infection

Objective To understand the distribution and drug resistance of pathogenic bacteria in respiratory tract infections,and to provide a basis for clinical treatment.Methods BioMerieux API System and Vitek Am System were both adopted for bacteria identification.K-B test was employed for analyzing antibiotic resistance,20eAUX for fungi detection and MIC for evaluation the resistance.Results A hundred and twenty strains collected from148 patients were isolated and the Gram-negative bacteria accounted for 66.7% of the total strains.The top five bacteria were respectively pseudomonas aeruginosa,Klebsiella pneumoniae,Escherichia coli,acinetobacter bacteria and enterobacter cloacae.The Gram-positive bacteria accounted for 23.3% of the total strains,mainly staphylococcus aureus,streptococcus Pneumoniae conjugate,Enterococcus faecalis and streptococcus pneumonia.Fungi took a proportion of 10.0%,mainly Candida albicans.The majority of gram-negative bacteria were sensitive to imipenem,penicillin,levofloxacin,with the drug resistance rates ranging from5.8%to 33.3%,while the drug resistance rates of cefazolin,Ceftriaxone and ampicillin were all above 50%.The Gram-positive bacteria were sensitive to vancomycin but not so sensitive to other antibiotics.Conclusion The respiratory tract infection pathogens in Jining hospital are mainly Gram-negative bacilli with relatively high drug resistance rate.Thus,Reasonable application of antibacterial agents should be emphasized.