Nosetiological analysis of drug resistance in lower respiratory tract infection.

Objective To understand the dist ribution and drug resistance of pathogenic bacteria in lower respiratory tract infection in our hospital and provide the basis for rational use of drugs.Method The bacteria identification system of France biomerieux BIOFOSUN was used for bacterial identification. Drug sensitivity test was performed with paper stip method.Result 253 strains of pathogenic bacteria were separated from the sputum sample of 1 160 cases,which including Klebsiella pneumoniae(83),Pseudomonas aeruginosa(57),Acinetobacter(29),Enterobacter cloacae(14),Serratia marcescens(13),Escherichia coli(10) and Staphylococcus aureus(5). The drug resistance rate of gram negative bacilli was the highest to sulfame. Conclusion The lower respiratory t ract in fections are mainly caused by gram negative bacilli. Clinicians must use antibiotics reasonably depending on the resultsof drug sensitivity tests.