Comparative study of Amiodarone and Lidocaine on fast ventricular arrhythmia during its acute period

Objective:To evaluate the curative effect and security of Amiodarone and Lidocaine on arrhythmia in its acute period.Methods:130 cases were divided into two groups as Amiodarone group with 70 cases and Lidocaine group with 60 cases.And the retrospective comparison and analysis of curative effect,mortality and adverse drug reactions of the two kind of medications on the treatment of fast ventricular arrhythmia in its acute period were performed.Results:On the treatment of fast ventricular arrhythmia during its acute period,Amiodarone was more effective than Lidocaine(P=0.017).And no statistical significance of mortality was obtained between these two groups.The incidence rate of adverse drug reactions were lower in Lidocaine group than the Amiodarone group(P=0.037).Conclusion:Amiodarone relatively has a good curative effect on the treatment of fast ventricular arrhythmia during its acute period,and it could be recommended as the first choice for the treatment.