An Experimental Study on the Anti-tumor Effects of Duhuojisheng Decoction in Tumor Bearing Mice

Objective:To study the anti-tumor effects of Duhuojisheng Decoction on mice bearing sarcoma 180 and its possible mechanism.Methods:S_(180) bearing mice as model,effects of Duhuojisheng Decoction on tumor weight and the pathological diagnosis of tumor tissue were investigated.Modified MTT assay was used to determine immunological function in bearing mice.Results:Duhuojisheng Decoction could markedly inhibit the tumor weight of S_(180),the rate of inhibition ranged from 32.45～43.75 percent.Duhuojisheng Decoction could prompt tumor tissue large area necrosis and inflammation cell infiltration,activate proliferating ability of T cells,markedly increase activity of natural killers(NK) and secretion of interleukin-2(IL-2).Conclusion:Duhuojisheng Decoction had anti-tumor effects by regulating immune system.