2008•Guiding Journal of Traditional Chinese Medicine and PharmacyRequires access
Immune Anti-tumor Effect of Shiquandabu Decoction and Jinlingzi Powder in Epatoma-xenograft Rats
YU Wang-yi
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Abstract
Objective: To observe immune anti-tumor effect of Shiquandabu decoction and Jinlingzi powder in hepatoma-xenograft rats.Methods: The hepatoma-xenograft rats was constructed as model,systematically observing the effects of Shiquandabu decoction and Jinlingzi powder on tumor weight and immune function of spleen cell.Results: The average anti-tumor rate of Shiquandabu decoction and Jinlingzi powder in hepatoma-xenograft rats achieved to 43.8%,and the tumor weight showed a relationship with the dosage of drugs,promoting markedly activity of NK and production level of IL-2,enhance phagocytosis of peritoneal macrophages.Conclusion: The mechanism,which Shiquandabu decoction and Jinlingzi powder resist tumor,maybe enhance cellular immune function in hepatoma-xenograft rats.