Distribution and drug resistance of bacteria isolated from blood specimens

Objective To investigate the distribution and drug resistance of pathogenic bacteria in blood culture and to conduct usage of antimicrobial agents in clinic.Methods The blood samples were cultivated in the BACTEFX system.Isolated colonies were identified and drug sensitivity was tested by Microscan WalkAway 96SI system.Results Strains of pathogenic bacteria were isolated from 5 879 blood specimens,the positive rate was 16.2%.Gram-positive and Gram-negative bacilli isolated accounted for 52.9% and 43.4%,respectively,and fungi for 3.7%.The most common pathogens were coagulase negative Staphylococcus,Escherichia coli,Staphylococcus aureus.No strains resistant to vancomycin was found in Gram-positive bacteria.Gram-negative bacilli were highly susceptible to imipenem.Conclusion There are many kinds of pathogens identified from blood culture,and the drug resistance rate is high.Clinicians should monitor the change of pathogens and trends of drug resistance in time in order to give the patient correct antibiotic therapy and to control cross-infection in hospitals.