Therapeutic evaluation of different schemes in the treatment of refractory wounds of hand and foot

Objective To observe the clinical efficacy of routine closed suction drainage (VSD), improved VSD, VSD combined with rhEGF in the treatment of refractory wounds of hand and foot. Methods Ninety-nine patients were randomly divided into group A (conventional VSD), group B (modified VSD), group C (VSD combined with rhEGF), each with 33 cases. The clinical efficacy, epithelialization time, healing time, drainage tube blockage rate, positive rate of drainage fluid culture, wound healing rate were observed. Results The total effective rate of group B and group C were significantly higher than that of group A (P0.05), but no significant difference was found between group B and group C (P0.05).The epithelialization time, wound healing time, positive rate of drainage fluid culture, drainage tube blockage rate of group B and group C were significantly less than those of group A, while the wound healing rate were higher than that of group A (p0.05), with no statistically significant difference between group B and group C (P0.05). Conclusion Compared with the conventional VSD, the improved VSD and VSD combined with rhEGF have a better curative effect in the treatment of refractory wounds of hand and foot. Improved VSD may alleviate congestion problems better during the VSD treatment, and VSD combined with rhEGF can promote wound healing, which are worthy of further study.