ScholarLens Back to search
2009•Zhongguo tangniaobing zazhiRequires access

The relationship between serum cystatin C and diabetic nephropathy

Chunhong Zhang

Open publisher page 0 citations

Abstract

Objective To investigate the relationship between serum cystatin C (Cys C) and type 2 diabetes mellitus(T2DM). Methods The 140 patients diagnosed as T2DM were chosen as case group. The 30 normal individuals were as control group. Urine protein was measured with radioimmunoassay. Cys C was determined by particle-enhanced nephelometry immune assay (PENIA). Results ①As compared with control group, the serum cys C increased markedly in case group[-(0.85±0.62) vs (0.45±0.08)mg/L]. ②The serum cys C was significantly higher in CDN group than in SDM group[(1.45±0.92) vs (0.58±0.17)mg/L]. ③The study showed AUC~(RCC) of cys C was larger than that of Scr, and similar to that of UAER. Conclusions Cys C could be used as sensitive indicator for damage in kidney of type 2 diabetes.

About this research paper

What this paper is about

Objective To investigate the relationship between serum cystatin C (Cys C) and type 2 diabetes mellitus(T2DM). Methods The 140 patients diagnosed as T2DM were chosen as case group. The 30 normal individuals were as control group. Urine protein was measured with radioimmunoassay. Cys C was determined by particle-enhanced nephelometry immune assay (PENIA). Results ①As compared with control group, the serum cys C increased markedly in case group[-(0.85±0.62) vs (0.45±0.08)mg/L]. ②The serum cys C was significantly higher in CDN group than in SDM group[(1.45±0.92) vs (0.58±0.17)mg/L]. ③The study showed AUC~(RCC) of cys C was larger than that of Scr, and similar to that of UAER. Conclusions Cys C could be used as sensitive indicator for damage in kidney of type 2 diabetes.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the relationship between serum cystatin C (Cys C) and type 2 diabetes mellitus(T2DM). Methods The 140 patients diagnosed as T2DM were chosen as case group. The 30 normal individuals were as control group. Urine protein was measured with radioimmunoassay. Cys C was determined by particle-enhanced nephelometry immune assay (PENIA). Results ①As compared with control group, the serum cys C increased markedly in case group[-(0.85±0.62) vs (0.45±0.08)mg/L]. ②The serum cys C was significantly higher in CDN group than in SDM group[(1.45±0.92) vs (0.58±0.17)mg/L]. ③The study showed AUC~(RCC) of cys C was larger than that of Scr, and similar to that of UAER. Conclusions Cys C could be used as sensitive indicator for damage in kidney of type 2 diabetes.

Key concepts: Nephelometry, Cystatin C, Diabetic nephropathy, Internal medicine, Radioimmunoassay, Diabetes mellitus, Urine, Endocrinology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The relationship between serum cystatin C and diabetic nephropathy — Research Paper | ScholarLens