2011Zhiye yu jiankangRequires access

Value of Detection of Serum Cystatin C for Renal Damage in Type 2 Diabetes Mellitus

Wen Ming

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Abstract

[Objective]To test and compare the levels of serum cystatin C(Cys C) and serum creatinine(Scr),study the clinical significance of Cys C detection for type 2 diabetes mellitus. [Methods]The levels of Cys C and Scr were detected in the type 2 diabetes mellitus group(123 cases) and healthy control group(104 cases),and the results of two groups were compared. [Results]The levels of Cys C and Scr of the type 2 diabetes mellitus group were significantly higher than that of the healthy control group(P0.01;P0.05).In the type 2 diabetes mellitus group,the positive rate of Cys C(65.85%) was higher than that of Scr(26.83%) significantly(P0.01).There was a significant positive correlation between Cys C and Scr(r=0.563). [Conclusion]The detection rate of Cys C is high in patients with type 2 diabetes mellitus group,and it can be used as a good serological indicator for early renal damage in type 2 diabetes mellitus.

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What this paper is about

[Objective]To test and compare the levels of serum cystatin C(Cys C) and serum creatinine(Scr),study the clinical significance of Cys C detection for type 2 diabetes mellitus. [Methods]The levels of Cys C and Scr were detected in the type 2 diabetes mellitus group(123 cases) and healthy control group(104 cases),and the results of two groups were compared. [Results]The levels of Cys C and Scr of the type 2 diabetes mellitus group were significantly higher than that of the healthy control group(P0.01;P0.05).In the type 2 diabetes mellitus group,the positive rate of Cys C(65.85%) was higher than that of Scr(26.83%) significantly(P0.01).There was a significant positive correlation between Cys C and Scr(r=0.563). [Conclusion]The detection rate of Cys C is high in patients with type 2 diabetes mellitus group,and it can be used as a good serological indicator for early renal damage in type 2 diabetes mellitus.

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Available abstract

[Objective]To test and compare the levels of serum cystatin C(Cys C) and serum creatinine(Scr),study the clinical significance of Cys C detection for type 2 diabetes mellitus. [Methods]The levels of Cys C and Scr were detected in the type 2 diabetes mellitus group(123 cases) and healthy control group(104 cases),and the results of two groups were compared. [Results]The levels of Cys C and Scr of the type 2 diabetes mellitus group were significantly higher than that of the healthy control group(P0.01;P0.05).In the type 2 diabetes mellitus group,the positive rate of Cys C(65.85%) was higher than that of Scr(26.83%) significantly(P0.01).There was a significant positive correlation between Cys C and Scr(r=0.563). [Conclusion]The detection rate of Cys C is high in patients with type 2 diabetes mellitus group,and it can be used as a good serological indicator for early renal damage in type 2 diabetes mellitus.

Key concepts: Type 2 Diabetes Mellitus, Cystatin C, Internal medicine, Medicine, Diabetes mellitus, Creatinine, Gastroenterology, Endocrinology

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