Expression of Prostatic Specific Membrane Antigen(PSMA) in Different Tisues

Objective To observe PSMA expression in different prostatic and non prostatic tissues,evaluate organ specificity of PSMA.Methods 111 cases of different prostatic tissue and 30 cases of non prostatic tissue were analysed by ABC immunohistochemical staining.Results Most of all the prostatic tissues showed PSMA expression,especially prostatic adenocarcinoma tissues;while none of the non prostatic tumor tissues showed PSMA expression.Conclusion PSMA is a new and better organ specific tumor marker,it may be expected to be used in diagnosis and immuno treament of prostatic adenocarcinoma.