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HPLC evaluation of uncertainty for determination of declofenac sodium in Chinese traditional medicine

Yuanchao Xie

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Abstract

Objective:To establish a method of uncertainty evaluation for the determination of declofenac sodium in chinese traditional medicine by HPLC.Method:The uncertainty was evaluated by a established mathematical model and the analysis of various factors affecting sample detection.Results:Each componets of uncertainty was calculated and the combined uncertainty was then finally obtained by synthesizing the uncertainties of various component variables.Conclusion:This method is appropriate to be used in the uncertainty evaluation for the determination of declofenac sodium in Chinese traditional medicine by HPLC.

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What this paper is about

Objective:To establish a method of uncertainty evaluation for the determination of declofenac sodium in chinese traditional medicine by HPLC.Method:The uncertainty was evaluated by a established mathematical model and the analysis of various factors affecting sample detection.Results:Each componets of uncertainty was calculated and the combined uncertainty was then finally obtained by synthesizing the uncertainties of various component variables.Conclusion:This method is appropriate to be used in the uncertainty evaluation for the determination of declofenac sodium in Chinese traditional medicine by HPLC.

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Available abstract

Objective:To establish a method of uncertainty evaluation for the determination of declofenac sodium in chinese traditional medicine by HPLC.Method:The uncertainty was evaluated by a established mathematical model and the analysis of various factors affecting sample detection.Results:Each componets of uncertainty was calculated and the combined uncertainty was then finally obtained by synthesizing the uncertainties of various component variables.Conclusion:This method is appropriate to be used in the uncertainty evaluation for the determination of declofenac sodium in Chinese traditional medicine by HPLC.

Key concepts: Chemistry, High-performance liquid chromatography, Chromatography, Measurement uncertainty, Sodium, Traditional Chinese medicine, Component (thermodynamics), Mathematics

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