2015•China Medicine and PharmacyRequires access

The effect and safety of remifentanil and fentanyl in general anesthesia applied to compare

Bao Yua

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Abstract

Objective To explore the effect and safety of remifentanil and fentanyl in general anesthesia applied to compare. Methods 65 cases of patients withvarious types of surgical operation choice as the research object From 2013 May to 2014 March in our hospital were collected and randomly divided all patients into observation group 33 cases and control group with 32 cases.Life sign changes were observed before and afteranesthesia in two groups of patients,while recording the wake,extubation time after stopping drug,operation time,anesthesia time,orientation recovery time were all observed. Results The observation group before and after anesthesia heart rate,systolic and diastolic blood pressure changes little(P 0.05);control group after anesthesia,heart rate,systolic and diastolic blood pressure was significantly higher than that of before anesthesia,significant difference(P 0.05).The control group after anesthesia,heart rate,systolic and diastolic blood pressure and Huiping higher than that of the control group(P 0.05).Comparison and the time of anesthesia operation time of twogroups of patients,no significant difference(P 0.05);and the observation group wake time and concentration response time was significantly shorter than that in the control group,the difference between the two groups was significant(P 0.05). Conclusion In anesthesia,remifentanil with fentanyl anesthesia has obvious curative effect,sufentanil can obviously improve the postoperative patients with speed,reduce the incidence of postoperative pain,worthy of clinical popularization and application.

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Objective To explore the effect and safety of remifentanil and fentanyl in general anesthesia applied to compare. Methods 65 cases of patients withvarious types of surgical operation choice as the research object From 2013 May to 2014 March in our hospital were collected and randomly divided all patients into observation group 33 cases and control group with 32 cases.Life sign changes were observed before and afteranesthesia in two groups of patients,while recording the wake,extubation time after stopping drug,operation time,anesthesia time,orientation recovery time were all observed. Results The observation group before and after anesthesia heart rate,systolic and diastolic blood pressure changes little(P 0.05);control group after anesthesia,heart rate,systolic and diastolic blood pressure was significantly higher than that of before anesthesia,significant difference(P 0.05).The control group after anesthesia,heart rate,systolic and diastolic blood pressure and Huiping higher than that of the control group(P 0.05).Comparison and the time of anesthesia operation time of twogroups of patients,no significant difference(P 0.05);and the observation group wake time and concentration response time was significantly shorter than that in the control group,the difference between the two groups was significant(P 0.05). Conclusion In anesthesia,remifentanil with fentanyl anesthesia has obvious curative effect,sufentanil can obviously improve the postoperative patients with speed,reduce the incidence of postoperative pain,worthy of clinical popularization and application.

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Available abstract

Objective To explore the effect and safety of remifentanil and fentanyl in general anesthesia applied to compare. Methods 65 cases of patients withvarious types of surgical operation choice as the research object From 2013 May to 2014 March in our hospital were collected and randomly divided all patients into observation group 33 cases and control group with 32 cases.Life sign changes were observed before and afteranesthesia in two groups of patients,while recording the wake,extubation time after stopping drug,operation time,anesthesia time,orientation recovery time were all observed. Results The observation group before and after anesthesia heart rate,systolic and diastolic blood pressure changes little(P 0.05);control group after anesthesia,heart rate,systolic and diastolic blood pressure was significantly higher than that of before anesthesia,significant difference(P 0.05).The control group after anesthesia,heart rate,systolic and diastolic blood pressure and Huiping higher than that of the control group(P 0.05).Comparison and the time of anesthesia operation time of twogroups of patients,no significant difference(P 0.05);and the observation group wake time and concentration response time was significantly shorter than that in the control group,the difference between the two groups was significant(P 0.05). Conclusion In anesthesia,remifentanil with fentanyl anesthesia has obvious curative effect,sufentanil can obviously improve the postoperative patients with speed,reduce the incidence of postoperative pain,worthy of clinical popularization and application.

Key concepts: Medicine, Fentanyl, Anesthesia, Remifentanil, Sufentanil, Blood pressure, Heart rate, Ephedrine

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