Clinical analysis of Bi-Level Positive Airway Pressure ventilation in the treatment of COPD at acute exacerbation phase combined with Type II respiratory failure

Objective To investigate the application value of Bi-Level Positive Airway Pressure(BiPAP) in treating acute exacerbation of chronic obstructive pulmonary disease(AECOPD) with Type Ⅱ respiratory failure.Methods 58 cases of AECOPD with Type Ⅱ respiratory failure were randomly assigned into treatment group(32 cases) and control group(26 cases).The control group was treated with standard therapy and the treatment group was given standard therapy and immediate BiPAP mode.Comparison was then made between the two groups for arterial blood gas,respiratory rate,heart rate,intubation rate,death rate and period of hospitalization.Results At 48 hours after the treatment it showed improvement in arterial blood gas analysis,respiratory rate and heart rate compared with the control group(P0.05).Intubation rate,death rate,and period of hospitalization were lower in the treatment group than those in the control group(P0.05).Conclusions BiPAP improves the arterial blood gas,respiratory rate,and heart rate of patients with AECOPD combined with Type Ⅱ respiratory failure.It decreases the Intubation rate,death rate,and period of hospitalization.Thus it is an effective method to treat AECOPD.