Clinical observation of capsule for invigorating qi and blood on increasing efficacy of chemotherapy and alleviating toxic effects induced by chemotherapy for lung cancer

Objective To observe the effects of capsule for invigorating qi and blood in the treatment of non-small cell lung cancer patients undergoing chemotherapy.Methods Non-small cell lung cancer patients were randomly divided into treatment group and control group.Both groups were treated by two cycles of gemcitabine plus cisplatin chemotherapy,which is using gemcitabine 1000 mg/m2 plus cisplatin 75 mg/m2 by intravenous once for the first day,repeated once every three weeks.Three weeks was a cycle.In the week before chemotherapy,treatment group was us ing capsule for invigorating qi and blood by oral,three capsules each time,three times a day,for eight weeks.Results Kamofsky score in treatment group increased more than control group,the difference between the two groups was sig nificant(P 0.05).Effective rate in the treatment group and control group were 42.9% and 34.3% respectively,but there was no significant difference(P 0.05).Compared with control group,the incidence of hemoglobin reducing in treatment group was significantly decreased(P 0.05).Conclusion The efficacy of capsule for invigorating qi and blood with GP regimen was similar to simple GP regimen in treatment of lung cancer,but the former can significantly improve quality of life of the patients,prevent bone marrow suppression,and increase hemoglobin levels.