2007•Unpublished venueRequires access
Effect of Strengthening the Spleen and Tonifying the Kidney on the Function and Apoptosis of Kidney in Rats after Exhaustive Exercise
WU Yu-qiang
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Abstract
Objective To study the effect and mechanism of strengthening the spleen and tonifying the kidney on the function and apoptosis of kidney in rats.Methods The 42 male SD rats were randomly divided into quiet control group,exhausted exercise group and strengthening the spleen and tonifying the kidney group.Twenty four hours after exhaustive exercise,the concentrations of blood urea nitrogen(BUN),serum creatinine and urinary protein were determined.The apoptosis in kidneys of rats was detected by TUNEL.The structure of kidney was observed in the HE stain.Results Comparing with the exhausted exercise group,the concen- trations of BUN,serum creatinine and apoptotic index were lower significantly(P0.05)and there wasn't necrosis of kidney tissues in the strengthening the spleen and tonifying the kidney group.Conclusion Strengthening the spleen and tonifying the kidney play a certain role in protecting the renal function by inhibiting apoptosis and decreasing necrosis of kidney tissues.