2007•Lishizhen Medicine and Materia Medica ResearchRequires access
The Effect to IL-6,TNF-α of Invigorating "Qi",Nourishing "Yin",Promoting Blood Circulation and Dispersing Phlegm Method to Insulin Resistance in T2DM Patients
JI Ju-liang
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Abstract
Objective The aim was to observe the effect to IL-6、TNF-αof invigorating Qi,nourishing Yin,promoting blood circulation and dispersing phlegm method of TCM to insulin resistance(IR) in T2DM patients.Methods The selected patients were randomly divided into treatment group and control group,each group has 20 patients.The treatment group patients took invigorating Qi,nourishing Yin,promoting blood circulation and dispersing phlegm formula,the control group patients took Rosiglitazone tablets.The BG,HbA1C,insulin,FINS,IL-6 and TNF-α between before treatment and after treatment were observed.IR was evaluated by FINS and ISI.Results There was no statistic significance for each observed targets before treatment between the treatment group and the control groups(P0.05).There was obvious significance after treatment compared with before treatment(P0.01),and there was no statistic significance after treatment between the two groups(P0.05).Conclusion Invigorating Qi,nourishing Yin,promoting blood circulation and dispersing phlegm method maybe improve IR by anti-inflammation.