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2001•The Chinese Journal of DermatovenereologyRequires access

Analysis of Antibiotic Resistance of Neisseria gonorrhoeae in Guangzhou, 1999

Ping Li

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Abstract

Objective To survey the antibiotic resistance and the prevalence of penicillinase-producing Neisseria gonor- rhoeae(PPNG) and high-level tetracycline resistant Neisseria gonorrhoeae(TRNG) in Guangzhou. Methods Minimum inhibitory concentrations(MIC) were determined using the agar dilution method and that of β-lactamase by paper iodin quantitative method. Results There were 9(5. 4% ) strains PPNG and 16(9. 6% ) strains TRNG in 167 strains Neisseriae gonorrhoeae. Resistant rates of ciprofloxacin was as much as 78. 4%. The high-level resistant stains(MIC≥16mg/L) were 37 (22. 2 % ). No resistance strain to ceftriaxone and specitinomycin, ceftriaxone susceptibility was improving. Conclusion The study showed that it is impor- tant to successively survey the antibiotic resistance of Neisseriae gonorrheae.

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Objective To survey the antibiotic resistance and the prevalence of penicillinase-producing Neisseria gonor- rhoeae(PPNG) and high-level tetracycline resistant Neisseria gonorrhoeae(TRNG) in Guangzhou. Methods Minimum inhibitory concentrations(MIC) were determined using the agar dilution method and that of β-lactamase by paper iodin quantitative method. Results There were 9(5. 4% ) strains PPNG and 16(9. 6% ) strains TRNG in 167 strains Neisseriae gonorrhoeae. Resistant rates of ciprofloxacin was as much as 78. 4%. The high-level resistant stains(MIC≥16mg/L) were 37 (22. 2 % ). No resistance strain to ceftriaxone and specitinomycin, ceftriaxone susceptibility was improving. Conclusion The study showed that it is impor- tant to successively survey the antibiotic resistance of Neisseriae gonorrheae.

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Available abstract

Objective To survey the antibiotic resistance and the prevalence of penicillinase-producing Neisseria gonor- rhoeae(PPNG) and high-level tetracycline resistant Neisseria gonorrhoeae(TRNG) in Guangzhou. Methods Minimum inhibitory concentrations(MIC) were determined using the agar dilution method and that of β-lactamase by paper iodin quantitative method. Results There were 9(5. 4% ) strains PPNG and 16(9. 6% ) strains TRNG in 167 strains Neisseriae gonorrhoeae. Resistant rates of ciprofloxacin was as much as 78. 4%. The high-level resistant stains(MIC≥16mg/L) were 37 (22. 2 % ). No resistance strain to ceftriaxone and specitinomycin, ceftriaxone susceptibility was improving. Conclusion The study showed that it is impor- tant to successively survey the antibiotic resistance of Neisseriae gonorrheae.

Key concepts: Neisseria gonorrhoeae, Microbiology, Ciprofloxacin, Tetracycline, Ceftriaxone, Antibiotics, Agar Dilution Method, Neisseria

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