Chordoid meningiomas:A case report and literature review

Objective: To explore the clinical and pathological features of chordoid meningioma.Methods: Histopathology and immunohistochemistry were used to study the morphological characteristics of chordoid meningioma,and the related literature was reviewed.Results: Lobuler and strip shaped tumor cells were seen in the mucoid matrix.The cytoplasm was hypochromic or oxychromatic.There were some droplets cells in the mucoid matrix which were similar to chordoma-like cells.Typical meningioma cells pattern was observed focally.The histochemical data showed that the alcian blue and periodic acid schiff(AB/PAS) staining was positive.Immunohistochemical data showed that the vimentin and epithelial menbrane antigen(EMA) were positive,the progesterone receptor(PR) was focal positive,while the pan cytokeratin(CKpan) and S-100 calcium binding protein were negative.Conclusion: Chordoma meningioma is rare.It needs to distinguish from chordoma,myxoid chondrosarcoma or metastatic mucinous adenocarcinoma.