2010Medical Journal of Chinese People's HealthRequires access

The treatment efficacy analysis of 40 obsessive-compulsive disorder with combined therapy

Lin Xiang-lin

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Abstract

Objective:To investigate the treatment efficacy of obsessive-compulsive disorder with combination therapy(quetiapine joint sertraline).Methods:80 patients with obsessive-compulsive disorder were randomly divided into two groups,respectively,alone sertraline group of 40 patients(control group),and sertraline combined quetiapine group of 40 patients(treatment group),treatment for 8 weeks.Using Yale-Brown Obsessive-Compulsive Disorder Scale(Y-BOCS),Hamilton Depression Rating Scale(HAMD) and treatment of the symptoms scale(TESS) evaluation of the efficacy and adverse reactions.Results: The effect of the treatment group is significant with less adverse reactions and significant efficiency difference between the two groups has statistically significant(P0.01).Conclusions: The treatment of obsessive-compulsive disorder with two drugs in combination has remarkable efficacy,better safety,which is worthy to be popularized.

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Objective:To investigate the treatment efficacy of obsessive-compulsive disorder with combination therapy(quetiapine joint sertraline).Methods:80 patients with obsessive-compulsive disorder were randomly divided into two groups,respectively,alone sertraline group of 40 patients(control group),and sertraline combined quetiapine group of 40 patients(treatment group),treatment for 8 weeks.Using Yale-Brown Obsessive-Compulsive Disorder Scale(Y-BOCS),Hamilton Depression Rating Scale(HAMD) and treatment of the symptoms scale(TESS) evaluation of the efficacy and adverse reactions.Results: The effect of the treatment group is significant with less adverse reactions and significant efficiency difference between the two groups has statistically significant(P0.01).Conclusions: The treatment of obsessive-compulsive disorder with two drugs in combination has remarkable efficacy,better safety,which is worthy to be popularized.

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Available abstract

Objective:To investigate the treatment efficacy of obsessive-compulsive disorder with combination therapy(quetiapine joint sertraline).Methods:80 patients with obsessive-compulsive disorder were randomly divided into two groups,respectively,alone sertraline group of 40 patients(control group),and sertraline combined quetiapine group of 40 patients(treatment group),treatment for 8 weeks.Using Yale-Brown Obsessive-Compulsive Disorder Scale(Y-BOCS),Hamilton Depression Rating Scale(HAMD) and treatment of the symptoms scale(TESS) evaluation of the efficacy and adverse reactions.Results: The effect of the treatment group is significant with less adverse reactions and significant efficiency difference between the two groups has statistically significant(P0.01).Conclusions: The treatment of obsessive-compulsive disorder with two drugs in combination has remarkable efficacy,better safety,which is worthy to be popularized.

Key concepts: Hamd, Sertraline, Obsessive compulsive, Hamilton depression scale, Quetiapine, Clinical efficacy, Rating scale, Treatment and control groups

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