Chromosomal analysis for 2600 cases genetic consultant in Luoyang area

Objective:To study the relationship between the abnormal karyotype and the disease with karyotype analysis.Methods:Chromosomes were prepared according to the human body lymphocyte culture method,and karyotype analysis were done after G-banding.Results:183 samples were detected in 2600 patients,the rate of abnormality is 8%.84 cases were trisomy 21 karyotype,24 cases were the transposition,16 cases were chromosome inversion,59 cases were sex chromosomal abnormalities and other abnormal karyotypes.Conclusion:Chromosome abnormality is a considerable reason for mental retardation,infertility,habitual abortion and deformity.Chromosome detection has an important sense to improve the human quality.