Analysis of Chromosomal Karyotype in 270 Chromosome Disease Children of Guiyang

Objective: To explore the feature of abnormal karyotype for children with chromosome disease in Guiyang. Methods: Totally 270 children with mental retardation,developmental disorders,birth defects and abnormal karyotype were studied by analyzing the peripheral blood chromosome karyotype in a major hospital of Guiyang City. Results: There were 101 cases of abnormal karyotype of chromosome and the abnormal rate was 37. 41%( 101 /270). Among the 101 cases of chromosomes aberrance,there were 83 cases of abnormal euchromosome karyotype( accounting for 30. 74% in total cases and 82. 18% in abnormal cases) while there were 18 cases of abnormal sex chromosome karyotype( accounting for 6. 67% in total cases and 17. 82% in abnormal cases). Conclusion: The abnormal euchromosome karyotypes predonminate in child chromosome disease in Guiyang.