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The clinical significance of hydrothorax cytology and immunocytochemistry in differential diagnosis of metastatic pulmonary adenocarcinoma and mesothelial cells

Jie Zhang

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Abstract

Objective:To expore the clinical significance of hydrothorax cytology and immunocytochemistry in differential diagnosis of metostatic pulmonary adenocarcinoma and mesothelial cells. Methods: A total of 96 hydrothorax cytology specimens were tested by HE stainning smears and cell blocks ,immunocytochemical staining was detected for cell block sections for CEA,CK,CR,TTF-1,Ki-67 and Vimentin. Results: Combinaed cytological characteristics with immunocytochemistry staining on 96 cases, 42 cases adenocarcinoma and 54 cases mesothelial cell were diagnosed. Conclusion: Combined detection of CEA,CK TTF-1,Ki-67,CR and Vimentin with cytology is a method for diffentiation between metastatic pulmonary adenocarcinoma and mesothelial cells.

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What this paper is about

Objective:To expore the clinical significance of hydrothorax cytology and immunocytochemistry in differential diagnosis of metostatic pulmonary adenocarcinoma and mesothelial cells. Methods: A total of 96 hydrothorax cytology specimens were tested by HE stainning smears and cell blocks ,immunocytochemical staining was detected for cell block sections for CEA,CK,CR,TTF-1,Ki-67 and Vimentin. Results: Combinaed cytological characteristics with immunocytochemistry staining on 96 cases, 42 cases adenocarcinoma and 54 cases mesothelial cell were diagnosed. Conclusion: Combined detection of CEA,CK TTF-1,Ki-67,CR and Vimentin with cytology is a method for diffentiation between metastatic pulmonary adenocarcinoma and mesothelial cells.

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Available abstract

Objective:To expore the clinical significance of hydrothorax cytology and immunocytochemistry in differential diagnosis of metostatic pulmonary adenocarcinoma and mesothelial cells. Methods: A total of 96 hydrothorax cytology specimens were tested by HE stainning smears and cell blocks ,immunocytochemical staining was detected for cell block sections for CEA,CK,CR,TTF-1,Ki-67 and Vimentin. Results: Combinaed cytological characteristics with immunocytochemistry staining on 96 cases, 42 cases adenocarcinoma and 54 cases mesothelial cell were diagnosed. Conclusion: Combined detection of CEA,CK TTF-1,Ki-67,CR and Vimentin with cytology is a method for diffentiation between metastatic pulmonary adenocarcinoma and mesothelial cells.

Key concepts: Immunocytochemistry, Pathology, Hydrothorax, Mesothelial Cell, Adenocarcinoma, Cytology, Medicine, Pleural effusion

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