ScholarLens Back to search
2006•Chinese Journal of Birth Health & HeredityRequires access

Study on expression of TNF - α (tumor necrosis factor alpha) and Caspase - 3 and association between them in placenta of pregnant women with preeclampsia.

Tan Fang

Open publisher page 0 citations

Abstract

Objective: To evaluate expression of TNF - α (tumor necrosis factor alpha) and Caspase - 3 and association between them in placenta of pregnant women with preeclampsia. Methods: Immunohistochemistry was employed on two groups of preeclampsia (PE) (40 cases in total) and control group (20 cases) to show the location, distribution and quantity of TNF-α and Caspase -3. Results: The quantity of TNF - α and Caspase - 3 in serious group of PE is significantly higher than in control group ( P 0. 01). Besides, the quantity of TNF - α and Caspase - 3 in serious group of PE is shown positive associativity (R=0. 698, P 0. 001). Conclusion: In preeclampsia, placenta may be one of an important source of TNF - α. The morbility of preeclampsia may be associated with the addition of trophocyte apoptosis be induced by TNF - α which be produced by placenta region.

About this research paper

What this paper is about

Objective: To evaluate expression of TNF - α (tumor necrosis factor alpha) and Caspase - 3 and association between them in placenta of pregnant women with preeclampsia. Methods: Immunohistochemistry was employed on two groups of preeclampsia (PE) (40 cases in total) and control group (20 cases) to show the location, distribution and quantity of TNF-α and Caspase -3. Results: The quantity of TNF - α and Caspase - 3 in serious group of PE is significantly higher than in control group ( P 0. 01). Besides, the quantity of TNF - α and Caspase - 3 in serious group of PE is shown positive associativity (R=0. 698, P 0. 001). Conclusion: In preeclampsia, placenta may be one of an important source of TNF - α. The morbility of preeclampsia may be associated with the addition of trophocyte apoptosis be induced by TNF - α which be produced by placenta region.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective: To evaluate expression of TNF - α (tumor necrosis factor alpha) and Caspase - 3 and association between them in placenta of pregnant women with preeclampsia. Methods: Immunohistochemistry was employed on two groups of preeclampsia (PE) (40 cases in total) and control group (20 cases) to show the location, distribution and quantity of TNF-α and Caspase -3. Results: The quantity of TNF - α and Caspase - 3 in serious group of PE is significantly higher than in control group ( P 0. 01). Besides, the quantity of TNF - α and Caspase - 3 in serious group of PE is shown positive associativity (R=0. 698, P 0. 001). Conclusion: In preeclampsia, placenta may be one of an important source of TNF - α. The morbility of preeclampsia may be associated with the addition of trophocyte apoptosis be induced by TNF - α which be produced by placenta region.

Key concepts: Preeclampsia, Tumor necrosis factor alpha, Placenta, Medicine, Immunohistochemistry, Apoptosis, Caspase 3, Pregnancy

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Study on expression of TNF - α (tumor necrosis factor alpha) and Caspase - 3 and association between them in placenta of pregnant women with preeclampsia. — Research Paper | ScholarLens