Relationship between glycated hemoglobin A1C,blood lipids level and carotid atherosclerosis in elderly patients with type 2 diabetes mellitus

Objective:To explore the relationship of glycated hemoglobin A1C(HbA1C) and blood lipids level with carotid atherosclerosis(AS) in elderly patients with tpye 2 diabetes mellitus(T2DM).Methods: Carotid ultrasound determined intima-media thickness(IMT),sixty-six elderly patients with T2DM were divided into group T2DM-AS and group T2DM.The levels of HbA1C、triglyceride(TG)、total cholesterol(TC)、highdensity lipoprotein-cholesterol(HDL-C)、lowdensity lipoprotein-cholesterol(LDL-C)and lipoprotein(a)were measured.Meanwhile,the results were compared with fourty elderly healthy persons.Results: HbA1C of both group T2DM-AS and T2DM were higher than that of control group.There were significant difference between the two group(P0.05).TC,TG,LDL-C,Lp(a)of group T2DM-AS were higher than those of group T2DM and control group.But there was no significant difference of above mentioned indexes between the group T2DM and control group(P0.05).In group T2DM-AS,IMT was positively correlated with HbA1C,TC,TG,LDL-C,Lp(a),IMT was negative correlated with HDL-C.Conclusions: HbA1C can aggregate the development of AS in elderly patients with T2DM.It could be beneficial for the precaution of AS in elderly patients with T2DM to control the levels of HbA1C and blood lipids.