2010China Medical HeraldRequires access

The comparison and analysis of Dinoprostone Suppositories and Oxytocin induction of labor in the term pregnancy

Su Qin

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Abstract

Objective:To observe the effect and safety of Dinoprostone Suppositories and Oxytocin induction of labor in the term pregnancy.Methods:Two groups of the same conditions,totally 180 cases were randomly selected and divided into two groups,with 90 cases in each group.The observation group was treated with Dinoprostone Suppository,and the control group was treated with intravenous infusion of low dose Oxytocin.Statistical analysis was applied to compare the cervical Bishop score,birth process,normal labor rate,newborn score and post-partum haemorrhage of the two groups.Results:12 hours after administered Dinoprostone Suppository,the cervical Bishop score of the observation group was significantly higher than that of the control group(P0.01);the 24 hours birth progress and normal labor rate of the observation group were significantly higher than those of the control group(P0.01);newborn score and post-partum haemorrhage of the two groups showed no significant difference(P0.05).Conclusion:The effect of Dinoprostone Suppository used in full-term pregnancy abortion is superior to intravenous oxytocin infusion,and it can be safely and effectively used in clinical work.

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Objective:To observe the effect and safety of Dinoprostone Suppositories and Oxytocin induction of labor in the term pregnancy.Methods:Two groups of the same conditions,totally 180 cases were randomly selected and divided into two groups,with 90 cases in each group.The observation group was treated with Dinoprostone Suppository,and the control group was treated with intravenous infusion of low dose Oxytocin.Statistical analysis was applied to compare the cervical Bishop score,birth process,normal labor rate,newborn score and post-partum haemorrhage of the two groups.Results:12 hours after administered Dinoprostone Suppository,the cervical Bishop score of the observation group was significantly higher than that of the control group(P0.01);the 24 hours birth progress and normal labor rate of the observation group were significantly higher than those of the control group(P0.01);newborn score and post-partum haemorrhage of the two groups showed no significant difference(P0.05).Conclusion:The effect of Dinoprostone Suppository used in full-term pregnancy abortion is superior to intravenous oxytocin infusion,and it can be safely and effectively used in clinical work.

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Available abstract

Objective:To observe the effect and safety of Dinoprostone Suppositories and Oxytocin induction of labor in the term pregnancy.Methods:Two groups of the same conditions,totally 180 cases were randomly selected and divided into two groups,with 90 cases in each group.The observation group was treated with Dinoprostone Suppository,and the control group was treated with intravenous infusion of low dose Oxytocin.Statistical analysis was applied to compare the cervical Bishop score,birth process,normal labor rate,newborn score and post-partum haemorrhage of the two groups.Results:12 hours after administered Dinoprostone Suppository,the cervical Bishop score of the observation group was significantly higher than that of the control group(P0.01);the 24 hours birth progress and normal labor rate of the observation group were significantly higher than those of the control group(P0.01);newborn score and post-partum haemorrhage of the two groups showed no significant difference(P0.05).Conclusion:The effect of Dinoprostone Suppository used in full-term pregnancy abortion is superior to intravenous oxytocin infusion,and it can be safely and effectively used in clinical work.

Key concepts: Medicine, Suppository, Dinoprostone, Oxytocin, Bishop score, Induction of labor, Pregnancy, Statistical significance

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