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Surveillance of Measles Antibody Level in Healthy Population and Observation on Serological Efficacy of Primary and Supplementary Immunization of Measles Vaccine in Shantou City

Xin Guo

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Abstract

This paper reported the results of measles antibody detection in 767 persons aged 0~39 years old in Shatuo city. The overall antibody positive rate was 77.57% and the antibody geometric mean titres (GMT) was 1:783. Seropositive rate of 1-12 years old age groups were the highest (85.71%~98.44%) than the other groups. After the age of 6, antibody GMT was shown to be middle and low level. The seropositive rate of measles antibody dropped along with the growth of age. 94 persons aged 0 year and 93 persons aged 5-7 years randomly selected from 767 persons were observed after vaccinating measles vaccine. The immune successful rate of them was 96.81% and 61.29% respectively. The GMT increased by 28.4 times and 3.1 times respectively. Whether basic immunization or reimmunization, there was a negative relationship between immunization successful rate and the measles antibody titer prior to immunization.

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What this paper is about

This paper reported the results of measles antibody detection in 767 persons aged 0~39 years old in Shatuo city. The overall antibody positive rate was 77.57% and the antibody geometric mean titres (GMT) was 1:783. Seropositive rate of 1-12 years old age groups were the highest (85.71%~98.44%) than the other groups. After the age of 6, antibody GMT was shown to be middle and low level. The seropositive rate of measles antibody dropped along with the growth of age. 94 persons aged 0 year and 93 persons aged 5-7 years randomly selected from 767 persons were observed after vaccinating measles vaccine. The immune successful rate of them was 96.81% and 61.29% respectively. The GMT increased by 28.4 times and 3.1 times respectively. Whether basic immunization or reimmunization, there was a negative relationship between immunization successful rate and the measles antibody titer prior to immunization.

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Available abstract

This paper reported the results of measles antibody detection in 767 persons aged 0~39 years old in Shatuo city. The overall antibody positive rate was 77.57% and the antibody geometric mean titres (GMT) was 1:783. Seropositive rate of 1-12 years old age groups were the highest (85.71%~98.44%) than the other groups. After the age of 6, antibody GMT was shown to be middle and low level. The seropositive rate of measles antibody dropped along with the growth of age. 94 persons aged 0 year and 93 persons aged 5-7 years randomly selected from 767 persons were observed after vaccinating measles vaccine. The immune successful rate of them was 96.81% and 61.29% respectively. The GMT increased by 28.4 times and 3.1 times respectively. Whether basic immunization or reimmunization, there was a negative relationship between immunization successful rate and the measles antibody titer prior to immunization.

Key concepts: Measles, Medicine, Immunization, Antibody, Measles vaccine, Titer, Serology, Population

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Surveillance of Measles Antibody Level in Healthy Population and Observation on Serological Efficacy of Primary and Supplementary Immunization of Measles Vaccine in Shantou City — Research Paper | ScholarLens