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RELATIONSHIP BETWEEN HELICOBACTER PYLORI(HP) AND PRECANCEROUS LESION OF GASTRIC MUCOSA

Zhang Xiu

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Abstract

To investigate the relationship between helicobacter Pylori(HP) and Precancerous Lesion of Gastric Mucosa, 2 987 cases of gastroduodenal disease were analysed. The results examined showed that HP\|positive lesions were 1 580 cases(52.8% of total cases). The incidences of atrophy,intestinal metoplasia and dysplasia were 22.7%,8.6%and 4.4% for HP\|positive, and 12.4%,6.5% and 2.8% for HP\|negative, respectively. The former was significantly higher than the latter, respectively( P 0.01 or 0.05). This suggests that the above\|mentioned 3 kinds of gastric precanerous lesions might relate to HP infection. The average age of HP\|positive lesion for atrophy, intestinal metoplasia and dysplasia were 46.8,47.0 and 44.3 respectively, having no distinct difference as compared with HP\|negative. In addition, a comparative analysis of, the degree of 3 kinds of precancerous lesion in both cases was made and no marked disparity was found.

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What this paper is about

To investigate the relationship between helicobacter Pylori(HP) and Precancerous Lesion of Gastric Mucosa, 2 987 cases of gastroduodenal disease were analysed. The results examined showed that HP\|positive lesions were 1 580 cases(52.8% of total cases). The incidences of atrophy,intestinal metoplasia and dysplasia were 22.7%,8.6%and 4.4% for HP\|positive, and 12.4%,6.5% and 2.8% for HP\|negative, respectively. The former was significantly higher than the latter, respectively( P 0.01 or 0.05). This suggests that the above\|mentioned 3 kinds of gastric precanerous lesions might relate to HP infection. The average age of HP\|positive lesion for atrophy, intestinal metoplasia and dysplasia were 46.8,47.0 and 44.3 respectively, having no distinct difference as compared with HP\|negative. In addition, a comparative analysis of, the degree of 3 kinds of precancerous lesion in both cases was made and no marked disparity was found.

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Available abstract

To investigate the relationship between helicobacter Pylori(HP) and Precancerous Lesion of Gastric Mucosa, 2 987 cases of gastroduodenal disease were analysed. The results examined showed that HP\|positive lesions were 1 580 cases(52.8% of total cases). The incidences of atrophy,intestinal metoplasia and dysplasia were 22.7%,8.6%and 4.4% for HP\|positive, and 12.4%,6.5% and 2.8% for HP\|negative, respectively. The former was significantly higher than the latter, respectively( P 0.01 or 0.05). This suggests that the above\|mentioned 3 kinds of gastric precanerous lesions might relate to HP infection. The average age of HP\|positive lesion for atrophy, intestinal metoplasia and dysplasia were 46.8,47.0 and 44.3 respectively, having no distinct difference as compared with HP\|negative. In addition, a comparative analysis of, the degree of 3 kinds of precancerous lesion in both cases was made and no marked disparity was found.

Key concepts: Helicobacter pylori, Lesion, Gastroenterology, Dysplasia, Medicine, Atrophy, Precancerous lesion, Gastric mucosa

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