Study of the relationship between C-reactive protein and severity coronary heart disease

AIM To explore the relationship between C-reactive protein (CRP) and the severity of coronary heart disease (CHD).METHODS: The plasma CRP concentrations were tested in 166 cases who underwent coronary angiography (CAG) (CHD was present in 86 patients and absent in 80 cases as normal control group), and results of the two groups and different numbers of diseased coronary vessels in CHD group were analyzed. RESULTS: The plasma CRP concentrations were 2293±198, 5126±508, 12969±1076 μg/L, respectively, for the normal control group and the stable angina group, the unstable angina group. The indices in the stable angina group and the unstable angina group were significantly higher than those of the normal control group ( *P*0.05, *P*0.01 respectively). In the CHD group, the plasma concentrations were, 5131±513, 7024±689, 11970±2075 μg/L, respectively,for the 1-vessel-disease group, the 2-vessel-disease group and the 3-vessel-disease group. The indices of the three groups were significantly higher than those of the normal control group (*P*0.01). CONCLUSION:CRP concentration was closely associated with CHD