Efficacy observation of invasive-non-invasive mechanical ventilation sequential therapy combined with aerosol inhalation in severe respiratory failure

Objective:To study the clinical effects of sequential non-invasive following short-term invasive mechanical ventilation on patients with severe respiratory failure.Methods:The study was divided into observation group and the control group.The patients from the two groups were given different treatment after pulmonary infection had been controlled.The invasive ventilation time,incidence of ventilator-associated pneumonia(VAP)and other items were recorded.Results:For observation group and the control group,the incidence of VAP was 9.6%(3 case) and51.7%(15 case) respectively,the total duration of mechanical ventilation was(12.9 ±2.8) d and(18.6±3.5) d respectively.The duration of hospitalization was(16.3±3.7) d and(25.3±3.8) d,respectively.Each index of two groups were significant difference(P0.05).Conclusion:Sequential non-invasive following short-term invasive mechanical ventilation at the time of pulmonary infection control(PIC) window may significantly shorten the duration of mechanical ventilation and hospitalization,reduce treatment costs and the incidence of VAP,and enhance the rescue success rate.