Detection of mitral annular velocity with quantitative tissue velocity imaging for assessment of left ventricular function in coronary artery disease patients

Objective To evaluate left ventricular function of coronary artery disease by detecting mitral annular velocity with quantitative tissue velocity imaging.Methods Fifty-two patients with coronary artery disease(CAD)confirmed by coronary arteriography and thirty-six normal control subjects were included in this study.Mitral annular velocity was assessed at six sites.Peak systolic velocity(Vs),peak early diastolic velocity(Ve),peak late diastolic velocity(Va)and cardiac function parameters including left ventricular ejection fraction(LVEF),left ventricular end-diastolic volume(LVEDV)and left ventricular end-systolic volume (LVESV) were measured in both CAD patients and normal subjects.In addition,the mean of Vs,Ve and Va were calculated. Results①In CAD group,LVEF,Vs,Ve and Va were significantly lower than those in normal control group(P0.01 ).However, LVESV and LVEDV were significantly larger than those in CAD group(P0.01 ).②In CAD group,there was positive correlation not only between LVEF and Ve-mean,Vs-mean(r=0.361,P0.01;r=0.578,P0.01)respectively,but also between Vs-mean and Ve-mean(r=0.584,P=0.0001).③Regard Vs-m5.04 cm/s as a diagnostic standard for CAD,the sensitivity,specificity and accuracy were 66.7 %,82.9% and 73.2 %,respectively.Conclusion Systolic function and diastolic function of regional myocardial and global myocardial wall are impaired in patients with CAD.QTVI is an easily reduplicative and effective method to evaluate left ventrieular function of coronary artery disease.Vs-m is an effective indicator for evaluating cardiac dysfunction.